2011年4月8日星期五

Experts teach you how to really understand ulcer

The traditional treatment of peptic ulcer and gastric acid is the inhibition of gastric acid secretion or. Old days of basic drugs, currently used Hz receptor inhibitors or other acid secretion inhibitors. Application of these acid-fast acid-suppressing drugs, is certainly conducive to the healing of ulcers, but these drugs have a common drawback, once the withdrawal, long blamed for ulcer recurrence. Therefore, some patients have intermittent medication, but some must be taken long-term maintenance dose. There are many more patients with ulcer disease has repeatedly made repeated.

Through analysis of gastric juice, duodenal ulcer, gastric acid secretion is too high; and gastric acid secretion in patients at increased only 16% of the normal gastric acid secretion in many patients, and some even lower than normal. This shows that the number of gastric acid secretion is not the important factor in the pathogenesis of gastric ulcer, and gastric mucosal defenses reduced, so that the relative increase in the role of gastric acid and other attacks may be the main reason for the formation of gastric ulcer.

Also since 1983, a new awareness of the Helicobacter pylori (referred to as HP), the pathogenesis of peptic ulcer, with a new understanding. Most experts believe that HP is one of the factors of peptic ulcer disease, but not the only factor. Gastric ulcer patients in the past that the higher is the incidence of factors, and now know that HP infection, the gastric antrum as the formation of HP urease release of ammonia, and ammonia, Department of alkaline, so that the secretion of gastrin in antral G cells no longer inhibited by gastric acid, so a large number of gastrin secretion, thus contributing to a large number of parietal cells in the body of stomach acid secretion. Therefore, excessive stomach acid is the result of HP infection. HP will also produce a variety of tox

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