Defined ulcer

Ulcer disease is a common chronic systemic diseases, were divided into gastric and duodenal ulcers, also known as peptic ulcer. It is called a peptic ulcer, because of previous gastric ulcer and duodenal ulcer that was due to gastric acid and pepsin digestion on the formation of mucous membrane itself, in fact, gastric acid and pepsin is only one of the main ulcer formation There are other reasons for the formation of ulcer disease. Gastric ulcer and duodenal ulcer as the etiology and clinical symptoms have many similarities, the doctor is sometimes difficult to distinguish between gastric ulcer or duodenal ulcer, it is often diagnosed as peptic ulcer or gastric ulcer . If you can clear in the stomach or duodenal ulcers, that can be directly diagnosed as gastric ulcer or duodenal ulcer.

Common symptoms

Upper abdominal pain, located in the xiphoid (solar plexus), the middle upper abdomen or around the sex was burning, gnawing or hunger, dull pain, tenderness or pain. But sometimes limited to the lower chest. After the pain will last half an hour to three hours. When sent waves of pain elimination, after the last few weeks of intermittent pain occurs after a short period of pain-free period. The diet-related pain, often due to hunger, taking medication, induced by acidic food or drink. Pain can be due to eating, drinking, taking basic food (eg bread) and remission. Other possible symptoms are heartburn, vomiting acidic water, belching, appetite loss, weight loss, anemia, occasional vomiting, the pain will ease after vomiting, black or tarry stools

Ulcer causes

1. Genetic factors, family history of gastric ulcer sometimes, especially children, have a family history of ulcer patients may account for 25% to 60%. Another blood type A blood type than the other people easily this disease.

2. Chemical factors long-term consumption of alcohol or long-term use of aspirin, corticosteroids and other drugs prone to cause disease occurs, in addition to long-term smoking and drinking tea may have a certain relationship.

3. Lifestyle factors, in some ulcer patients and doctors and other professional drivers, such as seems to be more common among people, possibly due to regular diet-related. Work can also be induced Benbingfasheng too tired.

4. Mental stress or anxiety factors, sentimental, excessive mental work is the disease predisposing factors. May be due to stimulation of vagus nerve, caused by excessive gastric acid secretion.

5. Marshall proved that H. pylori infection factor is the ulcer bacteria Roche ultimate culprit, rather than previously thought too much pressure, or caused by acidic food, so Marshall won the 2005 Nobel Prize for medicine and physiology.

6. Other factors in different countries, different regions of the incidence of the disease varied incidence in different seasons are not the same, that geography and climate are also important factors. Also the disease can also be in other primary disease, such as burns, severe traumatic brain injury, gastrinoma, hyperparathyroidism, emphysema, cirrhosis, renal failure, on the basis of the disease, the so-called "secondary ulcers" (secondary ulcer .) This may be related to gastrin, hypercalcemia, and over-excited about the vagus nerve.

7. The factors that contribute to ulcer formation of gastric acid and pepsin: gastric juice contains protease and hydrochloric acid, hydrochloric acid over a certain concentration of protein to the stomach by pepsin hydrolysis.

8. Against ulcer formation factor can digest pure acidic gastric juice is true of all living tissue, including the stomach, but stomach and duodenal mucosa under normal circumstances, do not soak in pure acidic gastric juice. More acid in saliva, food water, gastric mucus and in the dilution buffer, it is clear, mucus, mucosal immunity plays an important protective role.

9. The relationship between hormones and peptic ulcer caused by adrenal cortex hormones should be passionate ulcers, ulcers with diethylstilbestrol as more and non-specific effect.

10. Other factors such as blood type O blood group than those of other high collapse machines, certain drugs such as aspirin can stimulate the gastric mucosa, the normal secretion of gastric smoking.